The course has the objective to provide the knowledge to understand our metabolism, how this is controlled under normalcy and altered in
pathological conditions.
At the end of the course, the student must:
- know the main metabolic pathways, their regulation at the molecular and cellular level, and their integration;
- recognize the rationale that governs the intermediate metabolic fluxes;
- be conscious that perturbations in the structures of biological macromolecules, which carry out reactions and which are involved in the
regulation of metabolic pathways, are at the onset of pathological cellular and systemic conditions.
- know how specific hormonal cascades, via receptors binding and signal transduction, lead to a fine tuning of our metabolism at the whole
organism level.