The overall aim is to provide the theoretical and methodological tools that allow knowing the different approaches that characterize clinical psychophysiology, as well as the salient aspects concerning psychopathology and its diagnosis, favoring the development of critical skills. At the end of the course, the student will be able to know: a) how mind and body interact in influencing subjective experience, behavior, and psychological health; b) the main etiological models and the most recent neuroscientific paradigms used in the field of clinical psychophysiology; c) the neurobiological basis of the main mental disorders and their symptoms; d) the most innovative psychotherapeutic models; e) the main biomarkers and predictors of efficacy of psychotherapeutic approaches.