The course aims to provide the necessary knowledge to the design and management of safety and maintenance of industrial systems, considered as complex production systems. To this end, the course deals with the handling of hazardous phenomena that can occur in a productive activity, provides information on laws and existing good practice in this regard and introduces methodologies for systems analysis useful to anticipate and manage unexpected phenomena in the operation machinery, equipment and facilities. Particular emphasis is given to the services to guarantee the safety of any system, especially in view of some significant trends (facility management, global services and outsourcing).